Investigating Nutritional Strategies for Managing Dry Age-Related Macular Degeneration
As seasoned optometrists, we frequently receive inquiries from patients regarding effective strategies to protect or enhance their vision, particularly in relation to age-related conditions such as Macular degeneration. The importance of nutrition and supplementation in sustaining optimal eye health is paramount, and an increasing volume of clinical research underlines their essential role in managing dry age-related macular degeneration (AMD).
In this thorough assessment, we will compare two prominent products available in the Australian market: Macutec Once Daily and Blackmores Macu-Vision Plus.

Comprehending the Fundamentals of Macular Degeneration
Macular degeneration is a progressive condition that significantly compromises the macula, which is the central region of the retina responsible for delivering clear, high-resolution vision. This debilitating condition ranks among the leading causes of severe vision loss in Australia, affecting countless individuals each year.
There are two primary forms of macular degeneration:
- Dry Macular Degeneration
This is the predominant type, accounting for around 90% of all cases. It involves a gradual thinning of the macular tissue, resulting in a slow but consistent decline in central vision over time. - Wet Macular Degeneration
This form is less common but significantly more severe. It occurs when abnormal blood vessels develop and leak fluid or blood beneath the macula, often leading to sudden and irreversible vision loss without prompt medical intervention.
What Are the Consequences of Not Treating Macular Degeneration Effectively?
- Dry AMD may progress at a slow pace, yet if left untreated, it can culminate in considerable vision loss over an extended duration.
- Wet AMD necessitates immediate medical attention to avert permanent damage to central vision.
What Are the Standard Treatment Approaches for Macular Degeneration?
- Wet AMD is typically managed through injections aimed at inhibiting the growth of abnormal, leaky blood vessels.
- Dry AMD is treated through a blend of lifestyle modifications and nutritional supplements that adhere to the scientifically validated AREDS2 formula.
Why Is Following the AREDS2 Formula Vital for Effective Treatment?
The Age-Related Eye Disease Studies (AREDS and AREDS2) have transformed our understanding of how nutritional support can play a critical role in managing AMD. The second study, AREDS2, enhanced the composition of the supplements by:
- Removing beta-carotene, which has been associated with an elevated risk of lung cancer in smokers.
- Modifying zinc levels to safer, yet equally effective amounts.
- Incorporating lutein and zeaxanthin, two vital macular carotenoids.
The outcome? A safer and more effective approach to slowing the progression of dry AMD.


Which Supplements Align with AREDS2 Guidelines in Australia?
Two well-recognised supplement options include:
1. Macutec Once Daily (by Stiltec – Proudly Australian Made)
Key Ingredients That Align with AREDS2 Guidelines:
- Vitamin C – 500mg
- Vitamin E – 400 IU
- Zinc Oxide – 25mg
- Copper – 2mg
- Lutein – 10mg
- Zeaxanthin – 2mg
Recommended dosage: One tablet daily with food.
Fully complies with the AREDS2 formula
2. Blackmores Macu-Vision Plus
- Vitamin C – 250mg
- Vitamin E – 200 IU
- Zinc Oxide – 40mg
- Copper – 1mg
- Lutein – 5mg
- Zeaxanthin – 1mg
Recommended dosage: One tablet daily with food.
Contains only half the recommended dose of lutein and zeaxanthin as per AREDS2
What Are the Drawbacks of the Original Blackmores Macu-Vision?
This product lacks both lutein and zeaxanthin and does not adhere to AREDS2 guidelines in any manner. While it offers some antioxidant support, it fails to deliver the essential nutrients required for maintaining optimal macular health.
In-Depth Comparison: Macutec vs Macu-Vision Plus
| Ingredient | Macutec Once Daily | Macu-Vision Plus | AREDS2 Recommended Dosage |
|---|---|---|---|
| Vitamin C | 500 mg | 250 mg | 500 mg |
| Vitamin E | 400 IU (as dl-alpha tocopheryl acetate) | 200 IU | 400 IU |
| Zinc (as Zinc Oxide) | 25 mg | 40 mg | 80 mg* |
| Copper (as Cupric Oxide) | 2 mg | 1 mg | 2 mg |
| Lutein | 10 mg (FloraGLO® Lutein) | 5 mg | 10 mg |
| Zeaxanthin | 2 mg (Optisharp® Zeaxanthin) | 1 mg | 2 mg |
| Capsules per day | 1 softgel | 1 tablet | 1 dose |
| AREDS2 Formula Compliance | Complete Match |
Partial (half dose L/Z, low C/E) |
Based on NEI AREDS2 Formula |
*AREDS2 research indicated that lower zinc doses (25 mg) were equally effective and resulted in fewer side effects compared to higher amounts of 80 mg.
Ingredient Analysis and Insights:
- Lutein & Zeaxanthin: Macutec Once Daily precisely meets the AREDS2 recommendation (10mg Lutein, 2mg Zeaxanthin), whereas Blackmores Macu-Vision Plus provides only half of this.
- Zinc: Although Macutec employs a lower 25 mg Zinc dosage, AREDS2 findings demonstrated that this quantity was equally effective and linked to fewer side effects than higher levels.
- Vitamin E Composition: Macutec uses dl-alpha tocopherol; while AREDS2 utilised natural d-alpha, this form is a widely accepted alternative that does not significantly affect most users.
- Manufacturing Standards: Macutec is Australian-made under pharmaceutical GMP and features premium branded lutein (FloraGLO®) and zeaxanthin (Optisharp®), both of which were employed in the original AREDS2 trials.
Key Considerations for Supplement Selection:
Macutec is also Australian-made, incorporating premium branded carotenoids that are part of the AREDS2 study, designed for convenient once-per-day dosing.
Macutec Once Daily offers a precise alignment with the AREDS2 formula, containing full-strength lutein (10 mg) and zeaxanthin (2 mg) while minimising excessive zinc intake.
Macu-Vision Plus, despite being marketed as an AREDS-style supplement, delivers only half of the recommended L/Z dosage, lower antioxidant levels, and excess zinc that may be unnecessary for users.
Your Final Choice: Which Supplement Suits Your Needs Best?
Both supplements aim to decelerate the progression of dry macular degeneration, but only one fully complies with the AREDS2 formula: Macutec Essentials. It provides:
- Full-strength, evidence-based ingredients
- Clinically validated effectiveness
- Outstanding value and precise dosing
- Manufactured in Australia under high-quality standards
For these reasons, Eyes by Design exclusively stocks Macutec Essentials, which we confidently endorse to our patients across the Central Coast and beyond.
Available in-store or for delivery throughout Australia.
Seeking Expert Advice on Eye Health?
If you have queries regarding macular health, nutritional supplements, or your eligibility for nutritional treatments, please reach out to our knowledgeable team.
We provide personalised, expert guidance informed by the latest clinical research.
Call (02) 4369 8169
Visit us at Shop 6, Kincumber Centre, 39 Avoca Drive, Kincumber NSW 2251
Frequently Asked Questions About Macutec Once Daily vs Macu-Vision Plus
What Is the AREDS2 Formula and Why Is It Essential for Eye Health?
AREDS2 represents a clinically validated blend of vitamins and minerals that have been shown to slow the progression of dry age-related macular degeneration. This formula includes vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin. Supplements that adhere to this formula, such as Macutec Essentials, offer the most evidence-based protection for maintaining macular health.
What Is the Purpose of Macutec Once Daily in Eye Care?
Macutec Once Daily is meticulously designed to support eye health in individuals diagnosed with dry age-related macular degeneration. It is based on the findings from the AREDS2 clinical research and aims to decelerate the disease’s progression by safeguarding the macula from oxidative damage.
Can Supplements Like Macutec or Macu-Vision Cure Macular Degeneration?
These supplements cannot cure the condition. However, they can significantly slow the progression of dry macular degeneration and may assist in preserving vision for an extended duration. Early intervention and consistent usage are pivotal for achieving the best possible outcomes.
What Sets Macutec Once Daily Apart from Other Macular Supplements?
Macutec Once Daily contains all the validated AREDS2 components in a convenient once-daily capsule form. It employs high-quality lutein and zeaxanthin identical to those utilised in the clinical trials and is manufactured in Australia following stringent pharmaceutical Good Manufacturing Practice standards.
How Do Lutein and Zeaxanthin Enhance Overall Macular Health?
Lutein and zeaxanthin are natural pigments present in the macula. They play a vital role in forming the macular pigment, and adequate intake is associated with increased macular pigment density. This enhancement aids in filtering harmful blue light and shields retinal tissue from oxidative stress.
Which Supplement Is Most Suitable If I Already Have Advanced Dry Macular Degeneration?
Macutec Once Daily is the most appropriate choice if you seek an AREDS2-compliant supplement that contains full-strength ingredients. It is specifically formulated for patients diagnosed with moderate to advanced dry AMD who wish to decelerate its progression.
Citation
The insights and conclusions presented in this content are derived from the findings of the Age-Related Eye Disease Study 2 (AREDS2), conducted by the National Eye Institute, part of the National Institutes of Health. This study provides a comprehensive evaluation of the effectiveness of the AREDS2 supplement formulation in slowing the progression of age-related macular degeneration.
For further information, please consult the National Eye Institute’s publication regarding the AREDS2 study.
In-Depth Comparison: Macu-Vision Plus vs Macutec Once Daily for Managing Macular Degeneration
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